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human PDLIM2 shRNA silencing Adenovirus

Name 
Ad-h-PDLIM2-shRNA
Cat No 
shADV-218542
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PDLIM2.

shADV-218542
Ad-h-PDLIM2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PDLIM2 (PDZ and LIM domain 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
MYSTIQUE; SLIM
Description (Vector)
PDLIM2 encodes a member of the ALP subfamily of PDZ-LIM domain proteins. The encoded protein suppresses anchorage-dependent growth and promotes cell migration and adhesion through interactions with the actin cytoskeleton via the PDZ domain. The encoded protein is also a putative tumor suppressor protein, and decreased expression of this gene is associated with several malignancies including breast cancer and adult T-cell leukemia. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
64236
Gene Name (Vector)
PDZ and LIM domain 2
Gene Symbol
PDLIM2
HGNC ID
HGNC:13992
ORF Size (aa)
1059
ORF Size (bp)
1059 bp
RefSeq ID
NM_021630
RefSeq Synonyms
NM_198042, NM_176871, NM_021630, BC071774, BC021556,
Species
human
UniGene ID
Hs.632034

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.