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human PCSK5 shRNA silencing Adenovirus

Name 
Ad-h-PCSK5-shRNA
Cat No 
shADV-218413
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PCSK5.

shADV-218413
Ad-h-PCSK5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PCSK5 (proprotein convertase subtilisin/kexin type 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PC5; PC6; PC6A; SPC6
Description (Vector)
PCSK5 belongs to the subtilisin-like proprotein convertase family. The members of this family are proprotein convertases that process latent precursor proteins into their biologically active products. This encoded protein mediates posttranslational endoproteolytic processing for several integrin alpha subunits. It is thought to process prorenin, pro-membrane type-1 matrix metalloproteinase and HIV-1 glycoprotein gp160. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
5125
Gene Name (Vector)
proprotein convertase subtilisin/kexin type 5
Gene Symbol
PCSK5
HGNC ID
HGNC:8747
ORF Size (aa)
2742
ORF Size (bp)
2742 bp
RefSeq ID
NM_006200
RefSeq Synonyms
NM_006200, NM_001190482, BC012064,
Species
human
UniGene ID
Hs.368542

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.