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human PCDHGC3 shRNA silencing Adenovirus

Name 
Ad-h-PCDHGC3-shRNA
Cat No 
shADV-218367
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PCDHGC3.

shADV-218367
Ad-h-PCDHGC3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PCDHGC3 (protocadherin gamma subfamily C, 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PC43; PCDH-GAMMA-C3; PCDH2
Description (Vector)
PCDHGC3 is a member of the protocadherin gamma gene cluster, one of three related clusters tandemly linked on chromosome five. These gene clusters have an immunoglobulin-like organization, suggesting that a novel mechanism may be involved in their regulation and expression. The gamma gene cluster includes 22 genes divided into 3 subfamilies. Subfamily A contains 12 genes, subfamily B contains 7 genes and 2 pseudogenes, and the more distantly related subfamily C contains 3 genes. The tandem array of 22 large, variable region exons are followed by a constant region, containing 3 exons shared by all genes in the cluster. Each variable region exon encodes the extracellular region, which includes 6 cadherin ectodomains and a transmembrane region. The constant region exons encode the common cytoplasmic region. These neural cadherin-like cell adhesion proteins most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been described for the gamma cluster genes.
Gene ID
5098
Gene Name (Vector)
protocadherin gamma subfamily C, 3
Gene Symbol
PCDHGC3
HGNC ID
HGNC:8716
ORF Size (aa)
2805
ORF Size (bp)
2805 bp
RefSeq ID
NM_002588
RefSeq Synonyms
NM_032403, NM_032402, NM_002588, BC026218, BC019299, BC006439, BC004321,
Species
human
UniGene ID
Hs.368160

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.