human PCDH12 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PCDH12.
shADV-218321
Ad-h-PCDH12-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PCDH12 (protocadherin 12). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
VE-cadherin-2; VECAD2
Description (Vector)
PCDH12 belongs to the protocadherin gene family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing 6 cadherin repeats, a transmembrane domain and a cytoplasmic tail that differs from those of the classical cadherins. The gene localizes to the region on chromosome 5 where the protocadherin gene clusters reside. The exon organization of this transcript is similar to that of the gene cluster transcripts, notably the first large exon, but no significant sequence homology exists. The function of this cellular adhesion protein is undetermined but mouse protocadherin 12 does not bind catenins and appears to have no affect on cell migration or growth.
Gene ID
51294
Gene Name (Vector)
protocadherin 12
Gene Symbol
PCDH12
HGNC ID
HGNC:8657
ORF Size (aa)
3564
ORF Size (bp)
3564 bp
RefSeq ID
NM_016580
RefSeq Synonyms
NM_016580, BC052973, BC042634,
Species
human
UniGene ID
Hs.439474
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.