human PARVA shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PARVA.
shADV-218251
Ad-h-PARVA-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PARVA (parvin alpha). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
actopaxin; alpha-parvin; calponin-like integrin-linked kinase-binding protein; CH-ILKBP; matrix-remodeling-associated protein 2; MXRA2
Description (eCommerce)
Actopaxin is a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. Actopaxin is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival [taken from NCBI Entrez Gene (Gene ID: 55742)].
Description (Vector)
PARVA encodes a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. The encoded protein is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival.
Gene ID
55742
Gene Name (eCommerce)
parvin alpha
Gene Name (Vector)
parvin alpha
Gene Symbol
PARVA
HGNC ID
HGNC:14652
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1119
ORF Size (bp)
1119 bp
Protein Name (eCommerce)
Alpha-parvin
RefSeq ID
NM_018222
RefSeq Synonyms
NM_018222, BC016713, BC014535,
Research Areas
Angiogenesis,Cytoskeleton,Signal Transduction
Research Areas (Faceted)
cancer,cell_biology,developmental_biology,signal_transduction
Species
human
Target Sentence
Actopaxin is a member of the parvin family of actin-binding proteins. Parvins are associated with focal contacts and contain calponin homology domains that bind to actin filaments. Actopaxin is part of the integrin-linked kinase signaling complex and plays a role in cell adhesion, motility and survival [taken from NCBI Entrez Gene (Gene ID: 55742)].
UniGene ID
Hs.607144
UniProt ID (eCommerce)
Q9NVD7
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.