human PARL shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human PARL.
shADV-218228
Ad-h-PARL-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human PARL (presenilin associated rhomboid like). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PRO2207; PSARL; PSARL1; PSENIP2; RHBDS1
Description (Vector)
PARL encodes a mitochondrial integral membrane protein. Following proteolytic processing of this protein, a small peptide (P-beta) is formed and translocated to the nucleus. PARL may be involved in signal transduction via regulated intramembrane proteolysis of membrane-tethered precursor proteins. Variation in this gene has been associated with increased risk for type 2 diabetes. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
55486
Gene Name (Vector)
presenilin associated rhomboid like
Gene Symbol
PARL
HGNC ID
HGNC:18253
ORF Size (aa)
990
ORF Size (bp)
990 bp
RefSeq ID
NM_018622
RefSeq Synonyms
NM_018622, NM_001324438, NM_001324437, NM_001324436, NM_001037639, BC014058, BC003653,
Species
human
UniGene ID
Hs.478469
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.