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human PAK7 shRNA silencing Adenovirus

Name 
Ad-h-PAK7-shRNA
Cat No 
shADV-218160
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PAK5.

shADV-218160
Ad-h-PAK7-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PAK5 (p21 (RAC1) activated kinase 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
PAK7
Description (Vector)
PAK7 is a member of the PAK family of Ser/Thr protein kinases. PAK family members are known to be effectors of Rac/Cdc42 GTPases, which have been implicated in the regulation of cytoskeletal dynamics, proliferation, and cell survival signaling. This kinase contains a CDC42/Rac1 interactive binding (CRIB) motif, and has been shown to bind CDC42 in the presence of GTP. This kinase is predominantly expressed in brain. It is capable of promoting neurite outgrowth, and thus may play a role in neurite development. This kinase is associated with microtubule networks and induces microtubule stabilization. The subcellular localization of this kinase is tightly regulated during cell cycle progression. Alternatively spliced transcript variants encoding the same protein have been described.
Gene ID
57144
Gene Name (Vector)
p21 (RAC1) activated kinase 5
Gene Symbol
PAK5
HGNC ID
HGNC:15916
ORF Size (aa)
2160
ORF Size (bp)
2160 bp
RefSeq ID
NM_020341
RefSeq Synonyms
NM_177990, NM_020341, BC024179,
Species
human
UniGene ID
Hs.32539

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.