human PACSIN3 shRNA silencing Adenovirus

Name 
Ad-h-PACSIN3-shRNA
Cat No 
shADV-218110
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human PACSIN3.

shADV-218110
Ad-h-PACSIN3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human PACSIN3 (protein kinase C and casein kinase substrate in neurons 3). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
protein kinase C and casein kinase substrate in neurons protein 3; SDPIII; SH3 domain-containing protein 6511; syndapin III
Description (eCommerce)
PACSIN3 (protein kinase C and casein kinase substrate in neurons protein 3) is a member of the PACSIN family, a group of adaptor protein that regulate vesicle trafficking via cytoskeletal alterations. PACSIN3 is primarily expressed in skeletal muscle and heart and has been shown to be specifically involved in the trafficking of GLUT 1 in adipocytes.
Description (Vector)
PACSIN3 is a member of the protein kinase C and casein kinase substrate in neurons family. The encoded protein is involved in linking the actin cytoskeleton with vesicle formation. Alternative splicing results in multiple transcript variants.
Gene ID
29763
Gene Name (eCommerce)
protein kinase C and casein kinase substrate in neurons 3
Gene Name (Vector)
protein kinase C and casein kinase substrate in neurons 3
Gene Symbol
PACSIN3
HGNC ID
HGNC:8572
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1275
ORF Size (bp)
1275 bp
Protein Name (eCommerce)
Protein kinase C and casein kinase substrate in neurons protein 3
RefSeq ID
NM_016223
RefSeq Synonyms
NM_016223, NM_001184975, NM_001184974, BC011889, BC007914,
Research Areas
Cytoskeleton,Transport
Research Areas (Faceted)
cell_biology
Species
human
Target Sentence
PACSIN3 (protein kinase C and casein kinase substrate in neurons protein 3) is a member of the PACSIN family, a group of adaptor protein that regulate vesicle trafficking via cytoskeletal alterations. PACSIN3 is primarily expressed in skeletal muscle and heart and has been shown to be specifically involved in the trafficking of GLUT 1 in adipocytes.
UniGene ID
Hs.334639
UniProt ID (eCommerce)
Q9UKS6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.