human P2RX7 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human P2RX7.
shADV-218051
Ad-h-P2RX7-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human P2RX7 (purinergic receptor P2X 7). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
P2X7
Description (Vector)
The product of this gene belongs to the family of purinoceptors for ATP. This receptor functions as a ligand-gated ion channel and is responsible for ATP-dependent lysis of macrophages through the formation of membrane pores permeable to large molecules. Activation of this nuclear receptor by ATP in the cytoplasm may be a mechanism by which cellular activity can be coupled to changes in gene expression. Multiple alternatively spliced variants have been identified, most of which fit nonsense-mediated decay (NMD) criteria.
Gene ID
5027
Gene Name (Vector)
purinergic receptor P2X 7
Gene Symbol
P2RX7
HGNC ID
HGNC:8537
ORF Size (aa)
1278
ORF Size (bp)
1278 bp
RefSeq ID
NM_002562
RefSeq Synonyms
NM_002562, BC011913, BC007679,
Species
human
UniGene ID
Hs.507102
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.