human OXT shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human OXT.
shADV-218032
Ad-h-OXT-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human OXT (oxytocin/neurophysin I prepropeptide). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
OT; OT-NPI; OXT-NPI
Description (Vector)
There are two proteins encoded by this gene, oxytocin and neurophysin I. Oxytocin is posterior pituitary hormone which is synthesized as an inactive precursor in the hypothalamus along with its carrier protein neurophysin I. Together with neurophysin, it is packaged into neurosecretory vesicles and transported axonally to the nerve endings in the neurohypophysis, where it is either stored or secreted into the bloodstream. The precursor seems to be activated while it is being transported along the axon to the posterior pituitary. This hormone contracts smooth muscle during parturition and lactation. It is also involved in cognition, tolerance, adaptation and complex sexual and maternal behaviour, as well as in the regulation of water excretion and cardiovascular functions.
Gene ID
5020
Gene Name (Vector)
oxytocin/neurophysin I prepropeptide
Gene Symbol
OXT
HGNC ID
HGNC:8528
ORF Size (aa)
378
RefSeq ID
NM_000915
RefSeq Synonyms
NM_000915, BC101843, BC101841, BC069144,
Species
human
UniGene ID
Hs.113216
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.