human ORAI1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human ORAI1.
shADV-217916
Ad-h-ORAI1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human ORAI1 (ORAI calcium release-activated calcium modulator 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CRACM1; IMD9; ORAT1; TAM2; TMEM142A
Description (Vector)
ORAI1 is a membrane calcium channel subunit that is activated by the calcium sensor STIM1 when calcium stores are depleted. This type of channel is the primary way for calcium influx into T-cells. Defects in this gene are a cause of immune dysfunction with T-cell inactivation due to calcium entry defect type 1 (IDTICED1).
Gene ID
84876
Gene Name (Vector)
ORAI calcium release-activated calcium modulator 1
Gene Symbol
ORAI1
HGNC ID
HGNC:25896
ORF Size (aa)
906
ORF Size (bp)
906 bp
RefSeq ID
NM_032790
RefSeq Synonyms
NM_032790, BC075831, BC015369, BC013386,
Species
human
UniGene ID
Hs.55148
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.