human BNIP3L Over-expression AAV

Name 
AAV-h-BNIP3L
Cat No 
AAV-214278
Availability
4-5 weeks
Categories
AAV, Over-Expression

This is an AAV expressing Human BNIP3L.

AAV-214278
AAV-h-BNIP3L

Ready-to-use AAV expressing Human BNIP3L (BCL2 interacting protein 3 like). Available with optional GFP reporter or cell-specific promoter.

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Product Details

AAV Serotype
Available in AAV1, AAV2, AAV3, AAV5, AAV6, AAV8, AAV9, AAV-DJ, AAV-DJ8, AAV-DJ9 and other wildtype/synthetic AAV capsids
AAV ITR
AAV2
Promoter
CMV (default), or choose from 30 different ubiquitous or cell specific promoter
Reporter
none, optional GFP, CFP, YFP, RFP or mCherry
Storage Buffer
PBS/5% Glycerol
Viral Backbone
Recombinant AAV

Gene Reference Data

Alternate Names
adenovirus E1B19k-binding protein B5; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3A; BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like; BCL2/adenovirus E1B 19-kd protein-interacting protein 3a; BCL2/adenovirus E1B 19kDa interacting protein 3 like; BNIP3a; NIP3L; NIP-3-like protein X; NIP3-like protein X; NIX
Description (eCommerce)
BNIP3L (BCL2/adenovirus E1B 19kDa interacting protein 3-like) is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. BNIP3L interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. BNIP3L is a functional homolog of BNIP3, a proapoptotic protein. This protein may function simultaneously with BNIP3 and may play a role in tumor suppression [taken from NCBI Entrez Gene (GeneID: 665)].
Description (Vector)
BNIP3L is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. It interacts with the E1B 19 kDa protein, which protects cells from virally-induced cell death. The encoded protein also interacts with E1B 19 kDa-like sequences of BCL2, another apoptotic protector. This protein counteracts the apoptotic inducer BNIP3 and may play a role in tumor suppression.
Gene ID
665
Gene Name (eCommerce)
BCL2 interacting protein 3 like
Gene Name (Vector)
BCL2 interacting protein 3 like
Gene Symbol
BNIP3L
HGNC ID
HGNC:1085
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
660
ORF Size (bp)
660 bp
Protein Name (eCommerce)
BCL2/adenovirus E1B 19 kDa protein-interacting protein 3-like
RefSeq ID
NM_004331
RefSeq Synonyms
NM_004331, NM_001330491, BC009603, BC001559,
Research Areas
Apoptosis,Host-Virus Interactions,Mitochondrion,Response to Virus
Research Areas (Faceted)
cell_biology,immunology,infectious_disease
Species
human
Target Sentence
BNIP3L (BCL2/adenovirus E1B 19kDa interacting protein 3-like) is a member of the BCL2/adenovirus E1B 19 kd-interacting protein (BNIP) family. BNIP3L interacts with the E1B 19 kDa protein which is responsible for the protection of virally-induced cell death, as well as E1B 19 kDa-like sequences of BCL2, also an apoptotic protector. BNIP3L is a functional homolog of BNIP3, a proapoptotic protein. This protein may function simultaneously with BNIP3 and may play a role in tumor suppression [taken from NCBI Entrez Gene (GeneID: 665)].
UniGene ID
Hs.131226
UniProt ID (eCommerce)
O60238

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.