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human OAZ3 shRNA silencing Adenovirus

Name 
Ad-h-OAZ3-shRNA
Cat No 
shADV-217316
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human OAZ3.

shADV-217316
Ad-h-OAZ3-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human OAZ3 (ornithine decarboxylase antizyme 3). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AZ3; OAZ-t; TISP15
Description (Vector)
Ornithine decarboxylase catalyzes the conversion of ornithine to putrescine in the first and apparently rate-limiting step in polyamine biosynthesis. The ornithine decarboxylase antizymes play a role in the regulation of polyamine synthesis by binding to and inhibiting ornithine decarboxylase. Antizyme expression is auto-regulated by polyamine-enhanced translational frameshifting. In contrast to antizymes 1 and 2, which are widely expressed throughout the body, the expression of this gene product (antizyme 3) is restricted to testis germ cells, and thus it is a possible candidate for heritable forms of human male infertility. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
51686
Gene Name (Vector)
ornithine decarboxylase antizyme 3
Gene Symbol
OAZ3
HGNC ID
HGNC:8097
ORF Size (aa)
573
RefSeq ID
NM_016178
RefSeq Synonyms
NM_016178, NM_001301371, NM_001134939, BC073949,
Species
human
UniGene ID
Hs.713789

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.