human NSUN5 shRNA silencing Adenovirus

Name 
Ad-h-NSUN5-shRNA
Cat No 
shADV-217123
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human NSUN5.

shADV-217123
Ad-h-NSUN5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NSUN5 (NOP2/Sun RNA methyltransferase family member 5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
NOL1; NOL1R; NSUN5A; p120; p120(NOL1); WBSCR20; WBSCR20A
Description (Vector)
NSUN5 encodes a member of the evolutionarily conserved NOL1/NOP2/Sun domain family. The encoded protein may function as a DNA methyltransferase in the nucleus. NSUN5 is deleted in Williams syndrome, a multisystem developmental disorder caused by the deletion of contiguous genes at 7q11.23. Alternative splicing of this gene results in multiple transcript variants encoding different isoforms.
Gene ID
55695
Gene Name (Vector)
NOP2/Sun RNA methyltransferase family member 5
Gene Symbol
NSUN5
HGNC ID
HGNC:16385
ORF Size (aa)
1401
ORF Size (bp)
1401 bp
RefSeq ID
NM_018044
RefSeq Synonyms
NM_148956, NM_018044, NM_001168348, NM_001168347, BC008084,
Species
human
UniGene ID
Hs.647060

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.