human NR2C1 shRNA silencing Adenovirus

Name 
Ad-h-NR2C1-shRNA
Cat No 
shADV-217044
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human NR2C1.

shADV-217044
Ad-h-NR2C1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NR2C1 (nuclear receptor subfamily 2 group C member 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
nuclear receptor subfamily 2 group C member 1; nuclear receptor subfamily 2, group C isoform; orphan nuclear receptor TR2; Testicular receptor 2; TR2; TR2 nuclear hormone receptor
Description (eCommerce)
TR2 is an orphan nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes [taken from NCBI Entrez Gene (Gene ID: 7181].
Description (Vector)
NR2C1 encodes a nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes. Multiple alternatively spliced transcript variants have been described, but the full-length nature of some of these variants has not been determined.
Gene ID
7181
Gene Name (eCommerce)
nuclear receptor subfamily 2 group C member 1
Gene Name (Vector)
nuclear receptor subfamily 2 group C member 1
Gene Symbol
NR2C1
HGNC ID
HGNC:7971
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1404
ORF Size (bp)
1404 bp
Protein Name (eCommerce)
Nuclear receptor subfamily 2 group C member 1
RefSeq ID
NM_003297
RefSeq Synonyms
NM_003297, NM_001127362, NM_001032287, BC040141,
Research Areas
Gene Expression,Transcription Factor/Regulator,Zinc-finger
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
TR2 is an orphan nuclear hormone receptor characterized by a highly conserved DNA binding domain (DBD), a variable hinge region, and a carboxy-terminal ligand binding domain (LBD) that is typical for all members of the steroid/thyroid hormone receptor superfamily. This protein also belongs to a large family of ligand-inducible transcription factors that regulate gene expression by binding to specific DNA sequences within promoters of target genes [taken from NCBI Entrez Gene (Gene ID: 7181].
UniGene ID
Hs.707524
UniProt ID (eCommerce)
P13056

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.