human NPY shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NPY.
shADV-217017
Ad-h-NPY-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NPY (neuropeptide Y). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
PYY4
Description (Vector)
NPY encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases.
Gene ID
4852
Gene Name (Vector)
neuropeptide Y
Gene Symbol
NPY
HGNC ID
HGNC:7955
ORF Size (aa)
294
RefSeq ID
NM_000905
RefSeq Synonyms
NM_000905, BC029497,
Species
human
UniGene ID
Hs.1832
Recently Viewed Products
Ad-CMV-iCre
Cat No: 1045
Ad-CMV-Caspase 9 (DN)
Cat No: 1044
Ad-CMV-Rb
Cat No: 1043
Ad-CMV-p27
Cat No: 1042
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.