human NPPB shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NPPB.
shADV-216993
Ad-h-NPPB-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NPPB (natriuretic peptide B). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BNP
Description (Vector)
NPPB is a member of the natriuretic peptide family and encodes a secreted protein which functions as a cardiac hormone. The protein undergoes two cleavage events, one within the cell and a second after secretion into the blood. The protein's biological actions include natriuresis, diuresis, vasorelaxation, inhibition of renin and aldosterone secretion, and a key role in cardiovascular homeostasis. A high concentration of this protein in the bloodstream is indicative of heart failure. Mutations in this gene have been associated with postmenopausal osteoporosis.
Gene ID
4879
Gene Name (Vector)
natriuretic peptide B
Gene Symbol
NPPB
HGNC ID
HGNC:7940
ORF Size (aa)
405
RefSeq ID
NM_002521
RefSeq Synonyms
NM_002521, BC025785,
Species
human
UniGene ID
Hs.219140
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.