human NOX3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NOX3.
shADV-216924
Ad-h-NOX3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NOX3 (NADPH oxidase 3). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GP91-3; MOX-2
Description (Vector)
NOX3 encodes a member of the NOX family of NADPH oxidases. These enzymes have the capacity to generate superoxide and other reactive oxygen species (ROS) and transport electrons across the plasma membrane. The ROS generated by family members have been implicated in numerous biological functions including host defense, posttranlational processing of proteins, cellular signaling, regulation of gene expression, and cell differentiation. The protein encoded by this gene is expressed predominantly in the inner ear and is involved in the biogenesis of otoconia/otolith, which are crystalline structures of the inner ear involved in the perception of gravity.
Gene ID
50508
Gene Name (Vector)
NADPH oxidase 3
Gene Symbol
NOX3
HGNC ID
HGNC:7890
ORF Size (aa)
1707
ORF Size (bp)
1707 bp
RefSeq ID
NM_015718
RefSeq Synonyms
NM_015718, BC160172,
Species
human
UniGene ID
Hs.247776
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.