human NNT shRNA silencing Adenovirus

Name 
Ad-h-NNT-shRNA
Cat No 
shADV-216846
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human NNT.

shADV-216846
Ad-h-NNT-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NNT (nicotinamide nucleotide transhydrogenase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
GCCD4
Description (Vector)
NNT encodes an integral protein of the inner mitochondrial membrane. The enzyme couples hydride transfer between NAD(H) and NADP(+) to proton translocation across the inner mitochondrial membrane. Under most physiological conditions, the enzyme uses energy from the mitochondrial proton gradient to produce high concentrations of NADPH. The resulting NADPH is used for biosynthesis and in free radical detoxification. Two alternatively spliced variants, encoding the same protein, have been found for this gene.
Gene ID
23530
Gene Name (Vector)
nicotinamide nucleotide transhydrogenase
Gene Symbol
NNT
HGNC ID
HGNC:7863
ORF Size (aa)
3261
ORF Size (bp)
3261 bp
RefSeq ID
NM_182977
RefSeq Synonyms
NM_182977, NM_012343, NM_001331026, BC110544, BC110543,
Species
human
UniGene ID
Hs.482043

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.