human NLRP2 shRNA silencing Adenovirus

Name 
Ad-h-NLRP2-shRNA
Cat No 
shADV-216798
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human NLRP2.

shADV-216798
Ad-h-NLRP2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NLRP2 (NLR family pyrin domain containing 2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CLR19.9; NALP2; NBS1; PAN1; PYPAF2
Description (Vector)
NALP proteins, such as NALP2, are characterized by an N-terminal pyrin (MIM 608107) domain (PYD) and are involved in the activation of caspase-1 (CASP1; MIM 147678) by Toll-like receptors (see TLR4; MIM 603030). They may also be involved in protein complexes that activate proinflammatory caspases (Tschopp et al., 2003 (PubMed 12563287)).(supplied by OMIM, Mar 2008)
Gene ID
55655
Gene Name (Vector)
NLR family pyrin domain containing 2
Gene Symbol
NLRP2
HGNC ID
HGNC:22948
ORF Size (aa)
2541
ORF Size (bp)
2541 bp
RefSeq ID
NM_017852
RefSeq Synonyms
NM_017852, NM_001174083, NM_001174082, NM_001174081, BC039269, BC003592, BC001039,
Species
human
UniGene ID
Hs.369279

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.