human NHLRC1 shRNA silencing Adenovirus

Name 
Ad-h-NHLRC1-shRNA
Cat No 
shADV-216689
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human NHLRC1.

shADV-216689
Ad-h-NHLRC1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NHLRC1 (NHL repeat containing E3 ubiquitin protein ligase 1). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
50
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
bA204B7.2; EPM2A; EPM2B; MALIN
Description (Vector)
NHLRC1 is a single subunit E3 ubiquitin ligase. Laforin is polyubiquitinated by the encoded protein. Defects in this intronless gene lead to an accumulation of laforin and onset of Lafora disease, also known as progressive myoclonic epilepsy type 2 (EPM2).
Gene ID
378884
Gene Name (Vector)
NHL repeat containing E3 ubiquitin protein ligase 1
Gene Symbol
NHLRC1
HGNC ID
HGNC:21576
ORF Size (aa)
1188
ORF Size (bp)
1188 bp
RefSeq ID
NM_198586
RefSeq Synonyms
NM_198586, BC103890, BC103889, BC103888,
Species
human
UniGene ID
Hs.348351

Recently Viewed Products

AAV-r-CDKN1A

Cat No: AAV-294363

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.