human NFYB shRNA silencing Adenovirus

Name 
Ad-h-NFYB-shRNA
Cat No 
shADV-216665
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human NFYB.

shADV-216665
Ad-h-NFYB-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NFYB (nuclear transcription factor Y subunit beta). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
80
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CBF-A; CBF-B; HAP3; NF-YB
Description (Vector)
NFYB is one subunit of a trimeric complex, forming a highly conserved transcription factor that binds with high specificity to CCAAT motifs in the promoter regions in a variety of genes. This gene product, subunit B, forms a tight dimer with the C subunit, a prerequisite for subunit A association. The resulting trimer binds to DNA with high specificity and affinity. Subunits B and C each contain a histone-like motif. Observation of the histone nature of these subunits is supported by two types of evidence; protein sequence alignments and experiments with mutants.
Gene ID
4801
Gene Name (Vector)
nuclear transcription factor Y subunit beta
Gene Symbol
NFYB
HGNC ID
HGNC:7805
ORF Size (aa)
624
RefSeq ID
NM_006166
RefSeq Synonyms
NM_006166, BC007035, BC005317, BC005316,
Species
human
UniGene ID
Hs.84928

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.