human NDUFS6 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human NDUFS6.
shADV-216529
Ad-h-NDUFS6-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human NDUFS6 (NADH:ubiquinone oxidoreductase subunit S6). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CI-13kA; CI-13kD-A; CI13KDA
Description (Vector)
NDUFS6 encodes a subunit of the NADH:ubiquinone oxidoreductase (complex I), which is the first enzyme complex in the electron transport chain of mitochondria. This complex functions in the transfer of electrons from NADH to the respiratory chain. The subunit encoded by this gene is one of seven subunits in the iron-sulfur protein fraction. Mutations in this gene cause mitochondrial complex I deficiency, a disease that causes a wide variety of clinical disorders, including neonatal disease and adult-onset neurodegenerative disorders.
Gene ID
4726
Gene Name (Vector)
NADH:ubiquinone oxidoreductase subunit S6
Gene Symbol
NDUFS6
HGNC ID
HGNC:7713
ORF Size (aa)
375
RefSeq ID
NM_004553
RefSeq Synonyms
NM_004553, BC046155, BC038664,
Species
human
UniGene ID
Hs.408257
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.