human NDUFB5 shRNA silencing Adenovirus

Name
Ad-h-NDUFB5-shRNA

Cat No
shADV-216509

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human NDUFB5.

shADV-216509

Ad-h-NDUFB5-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NDUFB5 (NADH:ubiquinone oxidoreductase subunit B5). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

CISGDH; SGDH

Description (Vector)

NDUFB5 is a subunit of the multisubunit NADH:ubiquinone oxidoreductase (complex I). Mammalian complex I is composed of 45 different subunits. It locates at the mitochondrial inner membrane. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Three transcript variants encoding different isoforms have been found for this gene.

Gene ID

4711

Gene Name (Vector)

NADH:ubiquinone oxidoreductase subunit B5

Gene Symbol

NDUFB5

HGNC ID

HGNC:7700

ORF Size (aa)

414

RefSeq ID

NM_002492

RefSeq Synonyms

NM_002492, NM_001199958, NM_001199957, BC093071, BC009796, BC005271,

Species

human

UniGene ID

Hs.718447

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.