human NDUFA2 shRNA silencing Adenovirus

Name
Ad-h-NDUFA2-shRNA

Cat No
shADV-216476

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human NDUFA2.

shADV-216476

Ad-h-NDUFA2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NDUFA2 (NADH:ubiquinone oxidoreductase subunit A2). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

B8; CD14; CIB8

Description (Vector)

The encoded protein is a subunit of the hydrophobic protein fraction of the NADH:ubiquinone oxidoreductase (complex 1), the first enzyme complex in the electron transport chain located in the inner mitochondrial membrane, and may be involved in regulating complex I activity or its assembly via assistance in redox processes. Mutations in this gene are associated with Leigh syndrome, an early-onset progressive neurodegenerative disorder. Alternative splicing results in multiple transcript variants.

Gene ID

4695

Gene Name (Vector)

NADH:ubiquinone oxidoreductase subunit A2

Gene Symbol

NDUFA2

HGNC ID

HGNC:7685

ORF Size (aa)

300

RefSeq ID

NM_002488

RefSeq Synonyms

NM_002488, NM_001185012, BC003674,

Species

human

UniGene ID

Hs.534333

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.