human NCBP1 shRNA silencing Adenovirus

Name 
Ad-h-NCBP1-shRNA
Cat No 
shADV-216391
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human NCBP1.

shADV-216391
Ad-h-NCBP1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human NCBP1 (nuclear cap binding protein subunit 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
80 kDa nuclear cap-binding protein; CBP80; NCBP; NCBP 80 kDa subunit; nuclear cap binding protein subunit 1, 80kDa; nuclear cap-binding protein subunit 1; Sto1
Description (eCommerce)
Nuclear cap binding protein subunit 1 (NCBP1) is part of the cap-bnding protein complex that associates with the 5’ cap structure of mRNAs to facilitate transcript stability, splicing efficiency, and 3’end formation.
Description (Vector)
The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein promotes high-affinity mRNA-cap binding and associates with the CTD of RNA polymerase II. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay.
Gene ID
4686
Gene Name (eCommerce)
nuclear cap binding protein subunit 1
Gene Name (Vector)
nuclear cap binding protein subunit 1
Gene Symbol
NCBP1
HGNC ID
HGNC:7658
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2373
ORF Size (bp)
2373 bp
Protein Name (eCommerce)
Nuclear cap-binding protein subunit 1
RefSeq ID
NM_002486
RefSeq Synonyms
NM_002486, BC001450,
Research Areas
Gene Expression,Host-Virus Interactions,mRNA Binding,mRNA Processing,mRNA Splicing,mRNA Transport,RNA Binding,RNA Processing,RNA Transport,Spliceosome,Translational Control
Research Areas (Faceted)
genetics,transcription_translation,infectious_disease,cell_biology
Species
human
Target Sentence
Nuclear cap binding protein subunit 1 (NCBP1) is part of the cap-bnding protein complex that associates with the 5’ cap structure of mRNAs to facilitate transcript stability, splicing efficiency, and 3’end formation.
UniGene ID
Hs.686479
UniProt ID (eCommerce)
Q09161

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.