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human MYO18A shRNA silencing Adenovirus

Name 
Ad-h-MYO18A-shRNA
Cat No 
shADV-216203
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human MYO18A.

shADV-216203
Ad-h-MYO18A-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MYO18A (myosin XVIIIA). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
70
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
MAJN; molecule associated with JAK3 N-terminus; myosin 18A; myosin containing a PDZ domain; myosin containing PDZ domain; MYSPD; ZSP-A receptor subunit SP-R210 alphaS; SPR210; SP-R210; surfactant protein receptor SP-R210; unconventional myosin-XVIIIa
Description (eCommerce)
Myo18A/Myosin XVIIIA is an unconventional myosin that contains a lysine and glutamine (KE)-rich domain and a PDZ domain. The KE and PDZ domains appear to direct subcellular localization of the Myo18A variants. It is a dimeric actin binding protein that may play a role in the stabilization and organization of the actin cytoskeleton. Recently a cell surface form of Myo18A has been identified as the receptor for surfactant protein A, a lipid-associated lung collectin that mediates innate and adaptive immune responses in the lungs.
Gene ID
399687
Gene Name (eCommerce)
myosin XVIIIA
Gene Name (Vector)
myosin XVIIIA
Gene Symbol
MYO18A
HGNC ID
HGNC:31104
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
6009
ORF Size (bp)
6009 bp
Protein Name (eCommerce)
Unconventional myosin-XVIIIa
RefSeq ID
NM_078471
RefSeq Synonyms
NM_203318, NM_078471, NM_001346768, NM_001346767, NM_001346766, NM_001346765, BC039612,
Research Areas
Apoptosis,Cytoskeleton,FGF Signaling,Golgi Apparatus,Signal Transduction
Research Areas (Faceted)
cell_biology,signal_transduction
Species
human
Target Sentence
Myo18A/Myosin XVIIIA is an unconventional myosin that contains a lysine and glutamine (KE)-rich domain and a PDZ domain. The KE and PDZ domains appear to direct subcellular localization of the Myo18A variants. It is a dimeric actin binding protein that may play a role in the stabilization and organization of the actin cytoskeleton. Recently a cell surface form of Myo18A has been identified as the receptor for surfactant protein A, a lipid-associated lung collectin that mediates innate and adaptive immune responses in the lungs.
UniGene ID
Hs.708160
UniProt ID (eCommerce)
Q92614

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.