human MYBPC3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MYBPC3.
shADV-216131
Ad-h-MYBPC3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MYBPC3 (myosin binding protein C, cardiac). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
CMD1MM; CMH4; FHC; LVNC10; MYBP-C
Description (Vector)
MYBPC3 encodes the cardiac isoform of myosin-binding protein C. Myosin-binding protein C is a myosin-associated protein found in the cross-bridge-bearing zone (C region) of A bands in striated muscle. MYBPC3, the cardiac isoform, is expressed exclussively in heart muscle. Regulatory phosphorylation of the cardiac isoform in vivo by cAMP-dependent protein kinase (PKA) upon adrenergic stimulation may be linked to modulation of cardiac contraction. Mutations in MYBPC3 are one cause of familial hypertrophic cardiomyopathy.
Gene ID
4607
Gene Name (Vector)
myosin binding protein C, cardiac
Gene Symbol
MYBPC3
HGNC ID
HGNC:7551
ORF Size (aa)
3825
ORF Size (bp)
3825 bp
RefSeq ID
NM_000256
RefSeq Synonyms
NM_000256, BC151211, BC142685, BC136546, BC136543,
Species
human
UniGene ID
Hs.524906
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.