human MXD1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MXD1.
shADV-216103
Ad-h-MXD1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MXD1 (MAX dimerization protein 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
BHLHC58; MAD; MAD1
Description (Vector)
MXD1 encodes a member of the MYC/MAX/MAD network of basic helix-loop-helix leucine zipper transcription factors. The MYC/MAX/MAD transcription factors mediate cellular proliferation, differentiation and apoptosis. The encoded protein antagonizes MYC-mediated transcriptional activation of target genes by competing for the binding partner MAX and recruiting repressor complexes containing histone deacetylases. Mutations in this gene may play a role in acute leukemia, and the encoded protein is a potential tumor suppressor. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Gene ID
4084
Gene Name (Vector)
MAX dimerization protein 1
Gene Symbol
MXD1
HGNC ID
HGNC:6761
ORF Size (aa)
636
RefSeq ID
NM_002357
RefSeq Synonyms
NM_002357, NM_001202514, NM_001202513, BC143832, BC143831, BC117260, BC113531, BC098396, BC069433, BC069377,
Species
human
UniGene ID
Hs.468908
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.