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human MTR shRNA silencing Adenovirus

Name 
Ad-h-MTR-shRNA
Cat No 
shADV-216044
Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human MTR.

shADV-216044
Ad-h-MTR-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MTR (5-methyltetrahydrofolate-homocysteine methyltransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
cblG; HMAG; MS
Description (Vector)
MTR encodes the enzyme 5-methyltetrahydrofolate-homocysteine methyltransferase. This enzyme, also known as cobalamin-dependent methionine synthase, catalyzes the final step in methionine biosynthesis. Mutations in MTR have been identified as the underlying cause of methylcobalamin deficiency complementation group G.
Gene ID
4548
Gene Name (Vector)
5-methyltetrahydrofolate-homocysteine methyltransferase
Gene Symbol
MTR
HGNC ID
HGNC:7468
ORF Size (aa)
3798
ORF Size (bp)
3798 bp
RefSeq ID
NM_000254
RefSeq Synonyms
NM_001291940, NM_001291939, NM_000254, BC144097, BC144095, BC136440, BC130616,
Species
human
UniGene ID
Hs.498187

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About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.