human MSL3 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MSL3.
shADV-215922
Ad-h-MSL3-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MSL3 (male-specific lethal 3 homolog (Drosophila)). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MSL3L1
Description (Vector)
MSL3 encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. MSL3 can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8.
Gene ID
10943
Gene Name (Vector)
male-specific lethal 3 homolog (Drosophila)
Gene Symbol
MSL3
HGNC ID
HGNC:7370
ORF Size (aa)
1566
ORF Size (bp)
1566 bp
RefSeq ID
NM_006800
RefSeq Synonyms
NM_078629, NM_078628, NM_006800, NM_001282174, NM_001193270, BC031210,
Species
human
UniGene ID
Hs.655288
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.