human MRPS31 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MRPS31.
shADV-215867
Ad-h-MRPS31-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MRPS31 (mitochondrial ribosomal protein S31). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
IMOGN38; MRP-S31; S31mt
Description (Vector)
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. The 28S subunit of the mammalian mitoribosome may play a crucial and characteristic role in translation initiation. This gene encodes a 28S subunit protein that has also been associated with type 1 diabetes; however, its relationship to the etiology of this disease remains to be clarified. Pseudogenes corresponding to this gene have been found on chromosomes 3 and 13.
Gene ID
10240
Gene Name (Vector)
mitochondrial ribosomal protein S31
Gene Symbol
MRPS31
HGNC ID
HGNC:16632
ORF Size (aa)
1188
ORF Size (bp)
1188 bp
RefSeq ID
NM_005830
RefSeq Synonyms
NM_005830, BC022045,
Species
human
UniGene ID
Hs.154655
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.