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human MRPS23 shRNA silencing Adenovirus

Name 
Ad-h-MRPS23-shRNA
Cat No 
shADV-215860
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human MRPS23.

shADV-215860
Ad-h-MRPS23-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MRPS23 (mitochondrial ribosomal protein S23). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
28S ribosomal protein S23, mitochondrial; CGI-138; HSPC329; mitochondrial small ribosomal subunit protein mS23; MRP-S23; S23mt
Description (eCommerce)
28S ribosomal protein S23, mitochondrial, is encoded by the gene MRPS23. A 28S subunit protein of the mitochondrial ribosome (mitoribosome) [taken from NCBI Entrez Gene (Gene ID: 51649)].
Description (Vector)
Mammalian mitochondrial ribosomal proteins are encoded by nuclear genes and help in protein synthesis within the mitochondrion. Mitochondrial ribosomes (mitoribosomes) consist of a small 28S subunit and a large 39S subunit. They have an estimated 75% protein to rRNA composition compared to prokaryotic ribosomes, where this ratio is reversed. Another difference between mammalian mitoribosomes and prokaryotic ribosomes is that the latter contain a 5S rRNA. Among different species, the proteins comprising the mitoribosome differ greatly in sequence, and sometimes in biochemical properties, which prevents easy recognition by sequence homology. This gene encodes a 28S subunit protein. A pseudogene corresponding to this gene is found on chromosome 7p.
Gene ID
51649
Gene Name (eCommerce)
mitochondrial ribosomal protein S23
Gene Name (Vector)
mitochondrial ribosomal protein S23
Gene Symbol
MRPS23
HGNC ID
HGNC:14509
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
573
Protein Name (eCommerce)
28S ribosomal protein S23, mitochondrial
RefSeq ID
NM_016070
RefSeq Synonyms
NM_016070, BC000242,
Research Areas
Cytoskeleton,Mitochondrion,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
28S ribosomal protein S23, mitochondrial, is encoded by the gene MRPS23. A 28S subunit protein of the mitochondrial ribosome (mitoribosome) [taken from NCBI Entrez Gene (Gene ID: 51649)].
UniGene ID
Hs.5836
UniProt ID (eCommerce)
Q9Y3D9

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.