human MPZL1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MPZL1.
shADV-215738
Ad-h-MPZL1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MPZL1 (myelin protein zero like 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
immunoglobulin family transmembrane protein; MPZL1b; myelin protein zero-like protein 1; protein zero related; Protein zero-related; PZR; PZR1b; PZRa; PZRb
Description (eCommerce)
Protein zero-related (PZR) is a cell surface receptor involved in signal transduction processes. PZR recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. It is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O95297].
Gene ID
9019
Gene Name (eCommerce)
myelin protein zero like 1
Gene Name (Vector)
myelin protein zero like 1
Gene Symbol
MPZL1
HGNC ID
HGNC:7226
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
810
ORF Size (bp)
810 bp
Protein Name (eCommerce)
Myelin protein zero-like protein 1
RefSeq ID
NM_024569
RefSeq Synonyms
NM_024569, NM_003953, NM_001146191, BC007881,
Research Areas
EGFR Signaling,Immunology,Signal Transduction,T-cell Receptor Signaling
Research Areas (Faceted)
signal_transduction,immunology
Species
human
Target Sentence
Protein zero-related (PZR) is a cell surface receptor involved in signal transduction processes. PZR recruits PTPN11/SHP-2 to the cell membrane and is a putative substrate of PTPN11/SHP-2. It is a major receptor for concanavalin-A (ConA) and is involved in cellular signaling induced by ConA, which probably includes Src family tyrosine-protein kinases [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/O95297].
UniGene ID
Hs.603116
UniProt ID (eCommerce)
O95297
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.