human MNX1 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MNX1.
shADV-215619
Ad-h-MNX1-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MNX1 (motor neuron and pancreas homeobox 1). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
HB9; HLXB9; homeobox HB9; homeobox protein HB9; HOXHB9; motor neuron and pancreas homeobox protein 1; SCRA1
Description (eCommerce)
Homeobox protein HB9 (HLXB9) contains one homeobox DNA-binding domain. HLBX9 is encoded by the motor neuron and pancreas homeobox protein 1 (MNX1) gene. Mutations in MNX1 are the cause of Currarino syndrome and result in presacral tumor, sacral agenesis, and anorectal malformation.
Description (Vector)
MNX1 encodes a nuclear protein, which contains a homeobox domain and is a transcription factor. Mutations in this gene result in Currarino syndrome, an autosomic dominant congenital malformation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Gene ID
3110
Gene Name (eCommerce)
motor neuron and pancreas homeobox 1
Gene Name (Vector)
motor neuron and pancreas homeobox 1
Gene Symbol
MNX1
HGNC ID
HGNC:4979
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1206
ORF Size (bp)
1206 bp
Protein Name (eCommerce)
Motor neuron and pancreas homeobox protein 1
RefSeq ID
NM_005515
RefSeq Synonyms
NM_005515, NM_001165255, BC160126,
Research Areas
Axon Guidance,Immunology,Neurobiology,Neurodevelopment,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,developmental_biology,immunology,neurobiology,transcription_translation
Species
human
Target Sentence
Homeobox protein HB9 (HLXB9) contains one homeobox DNA-binding domain. HLBX9 is encoded by the motor neuron and pancreas homeobox protein 1 (MNX1) gene. Mutations in MNX1 are the cause of Currarino syndrome and result in presacral tumor, sacral agenesis, and anorectal malformation.
UniGene ID
Hs.37035
UniProt ID (eCommerce)
P50219
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.