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human MKNK1 shRNA silencing Adenovirus

Name 
Ad-h-MKNK1-shRNA
Cat No 
shADV-215503
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human MKNK1.

shADV-215503
Ad-h-MKNK1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MKNK1 (MAP kinase interacting serine/threonine kinase 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
MNK1
Description (Vector)
MKNK1 encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene.
Gene ID
8569
Gene Name (Vector)
MAP kinase interacting serine/threonine kinase 1
Gene Symbol
MKNK1
HGNC ID
HGNC:7110
ORF Size (aa)
1398
ORF Size (bp)
1398 bp
RefSeq ID
NM_003684
RefSeq Synonyms
NM_198973, NM_003684, NM_001135553, BC002755,
Species
human
UniGene ID
Hs.371594

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.