human MIOS shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MIOS.
shADV-215476
Ad-h-MIOS-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MIOS (meiosis regulator for oocyte development). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
GATOR complex protein MIOS; H_DJ1159O04.1; MIO; Missing oocyte meiosis regulator homolog; missing oocyte, meiosis regulator, homolog; Sea4; WD repeat-containing protein mio; WUGSC:H_DJ1159O04.1; Yulink
Description (eCommerce)
MIOS is a component of the GATOR2 complex. It inhibits GATOR1 complex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NXC5].
Gene ID
54468
Gene Name (eCommerce)
meiosis regulator for oocyte development
Gene Name (Vector)
meiosis regulator for oocyte development
Gene Symbol
MIOS
HGNC ID
HGNC:21905
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
2628
ORF Size (bp)
2628 bp
Protein Name (eCommerce)
WD repeat-containing protein mio
RefSeq ID
NM_019005
RefSeq Synonyms
NM_019005, BC140834, BC140833,
Research Areas
Cell Biology,Translational Control
Research Areas (Faceted)
cell_biology,transcription_translation
Species
human
Target Sentence
MIOS is a component of the GATOR2 complex. It inhibits GATOR1 complex, an inhibitor of the amino acid-sensing branch of the TORC1 pathway [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NXC5].
UniGene ID
Hs.520215
UniProt ID (eCommerce)
Q9NXC5
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.