human MCOLN2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MCOLN2.
shADV-215198
Ad-h-MCOLN2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MCOLN2 (mucolipin 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
TRP-ML2; TRPML2
Description (Vector)
Mucolipins constitute a family of cation channel proteins with homology to the transient receptor potential superfamily. In mammals, the mucolipin family includes 3 members, MCOLN1 (MIM 605248), MCOLN2, and MCOLN3 (MIM 607400), that exhibit a common 6-membrane-spanning topology. Homologs of mammalian mucolipins exist in Drosophila and C. elegans. Mutations in the human MCOLN1 gene cause mucolipodosis IV (MIM 262650) (Karacsonyi et al., 2007 (PubMed 17662026)).(supplied by OMIM, Sep 2009)
Gene ID
255231
Gene Name (Vector)
mucolipin 2
Gene Symbol
MCOLN2
HGNC ID
HGNC:13357
ORF Size (aa)
1701
ORF Size (bp)
1701 bp
RefSeq ID
NM_153259
RefSeq Synonyms
NM_153259, NM_001330647, BC104893, BC104891,
Species
human
UniGene ID
Hs.591446
Recently Viewed Products
Ad-CMV-Luc
Cat No: 1000
Ad-CMV-Akt1 (Myr)
Cat No: 1020
Ad-CMV-Akt1 (dn)
Cat No: 1021
Ad-CMV-Akt1 (wt)
Cat No: 1022
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.