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human MC3R shRNA silencing Adenovirus

Name 
Ad-h-MC3R-shRNA
Cat No 
shADV-215135
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human MC3R.

shADV-215135
Ad-h-MC3R-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MC3R (melanocortin 3 receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
BMIQ9; MC3; MC3-R; OB20; OQTL
Description (Vector)
MC3R encodes a G-protein-coupled receptor for melanocyte-stimulating hormone and adrenocorticotropic hormone that is expressed in tissues other than the adrenal cortex and melanocytes. MC3R maps to the same region as the locus for benign neonatal epilepsy. Mice deficient for this gene have increased fat mass despite decreased food intake, suggesting a role for this gene product in the regulation of energy homeostasis. Mutations in this gene are associated with a susceptibility to obesity in humans.
Gene ID
4159
Gene Name (Vector)
melanocortin 3 receptor
Gene Symbol
MC3R
HGNC ID
HGNC:6931
ORF Size (aa)
1083
ORF Size (bp)
1083 bp
RefSeq ID
NM_019888
RefSeq Synonyms
NM_019888, BC098351, BC098169, BC096737, BC096702, BC069599, BC069105,
Species
human
UniGene ID
Hs.248018

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.