human MBNL2 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MBNL2.
shADV-215107
Ad-h-MBNL2-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MBNL2 (muscleblind like splicing regulator 2). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
MBLL; MBLL39; PRO2032
Description (Vector)
MBNL2 is a member of the muscleblind protein family which was initially described in Drosophila melanogaster. MBNL2 encodes a C3H-type zinc finger protein that modulates alternative splicing of pre-mRNAs. Muscleblind proteins bind specifically to expanded dsCUG RNA but not to normal size CUG repeats and may thereby play a role in the pathophysiology of myotonic dystrophy. Several alternatively spliced transcript variants have been described but the full-length natures of only some have been determined.
Gene ID
10150
Gene Name (Vector)
muscleblind like splicing regulator 2
Gene Symbol
MBNL2
HGNC ID
HGNC:16746
ORF Size (aa)
1086
ORF Size (bp)
1086 bp
RefSeq ID
NM_207304
RefSeq Synonyms
NM_207304, NM_144778, NM_001306070, BC104040, BC104039, BC104038,
Species
human
UniGene ID
Hs.657347
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.