human MARCKS shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human MARCKS.
shADV-215031
Ad-h-MARCKS-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human MARCKS (myristoylated alanine rich protein kinase C substrate). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
80K-L; MACS; PKCSL; PRKCSL
Description (Vector)
MARCKS is a substrate for protein kinase C. It is localized to the plasma membrane and is an actin filament crosslinking protein. Phosphorylation by protein kinase C or binding to calcium-calmodulin inhibits its association with actin and with the plasma membrane, leading to its presence in the cytoplasm. The protein is thought to be involved in cell motility, phagocytosis, membrane trafficking and mitogenesis.
Gene ID
4082
Gene Name (Vector)
myristoylated alanine rich protein kinase C substrate
Gene Symbol
MARCKS
HGNC ID
HGNC:6759
ORF Size (aa)
999
ORF Size (bp)
999 bp
RefSeq ID
NM_002356
RefSeq Synonyms
NM_002356, BC089040,
Species
human
UniGene ID
Hs.712721
About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.