human MARCH7 shRNA silencing Adenovirus

Name
Ad-h-MARCH7-shRNA

Cat No
shADV-215026

Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human MARCH7.

shADV-215026

Ad-h-MARCH7-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human MARCH7 (membrane associated ring-CH-type finger 7). Available with optional GFP reporter or cell-specific promoter.

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Vector Designer

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Knockdown (%)

shRNA Validated

Yes

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

AXO; AXOT; MARCH-VII; RNF177

Description (Vector)

MARCH7 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH proteins add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments (Bartee et al., 2004 (PubMed 14722266)).(supplied by OMIM, Mar 2010)

Gene ID

64844

Gene Name (Vector)

membrane associated ring-CH-type finger 7

Gene Symbol

7-Mar

HGNC ID

HGNC:17393

ORF Size (aa)

2115

ORF Size (bp)

2115 bp

RefSeq ID

NM_022826

RefSeq Synonyms

NM_022826, NM_001282807, NM_001282806, NM_001282805, BC065014,

Species

human

UniGene ID

Hs.529272

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.