human LTBR shRNA silencing Adenovirus

Name 
Ad-h-LTBR-shRNA
Cat No 
shADV-214667
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human LTBR.

shADV-214667
Ad-h-LTBR-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human LTBR (lymphotoxin beta receptor). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
D12S370; LT-BETA-R; lymphotoxin B receptor; lymphotoxin beta receptor (TNFR superfamily, member 3); Lymphotoxin-beta receptor; TNFCR; TNFR2-RP; TNFR3; TNF-RIII; TNF-R-III; TNFR-III; TNFR-RP; TNFRSF3; tumor necrosis factor C receptor; tumor necrosis factor receptor 2-related protein; tumor necrosis factor receptor superfamily member 3; tumor necrosis factor receptor type III
Description (eCommerce)
Tumor necrosis factor receptor superfamily member 3, also known as lymphotoxin-beta receptor, is encoded for by the gene LTBR. A member of the tumor necrosis factor receptor superfamily, the major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death [taken from NCBI Entrez Gene (Gene ID: 4055)].
Description (Vector)
LTBR encodes a member of the tumor necrosis factor receptor superfamily. The major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death. Activity of this receptor has also been linked to carcinogenesis. Alternatively spliced transcript variants encoding multiple isoforms have been observed.
Gene ID
4055
Gene Name (eCommerce)
lymphotoxin beta receptor
Gene Name (Vector)
lymphotoxin beta receptor
Gene Symbol
LTBR
HGNC ID
HGNC:6718
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
1308
ORF Size (bp)
1308 bp
Protein Name (eCommerce)
Tumor necrosis factor receptor superfamily member 3
RefSeq ID
NM_002342
RefSeq Synonyms
NM_002342, NM_001270987, BC026262,
Research Areas
Apoptosis,Cancer,HIF-1 Signaling,Host-Virus Interactions,Immunology,JNK Signaling,NF-kB Signaling,Signal Transduction,Viral Carcinogenesis
Research Areas (Faceted)
cancer,signal_transduction,cell_biology,infectious_disease,immunology,signal_transduction,cancer,infectious_disease
Species
human
Target Sentence
Tumor necrosis factor receptor superfamily member 3, also known as lymphotoxin-beta receptor, is encoded for by the gene LTBR. A member of the tumor necrosis factor receptor superfamily, the major ligands of this receptor include lymphotoxin alpha/beta and tumor necrosis factor ligand superfamily member 14. The encoded protein plays a role in signalling during the development of lymphoid and other organs, lipid metabolism, immune response, and programmed cell death [taken from NCBI Entrez Gene (Gene ID: 4055)].
UniGene ID
Hs.1116
UniProt ID (eCommerce)
P36941

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.