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human LSS shRNA silencing Adenovirus

Name 
Ad-h-LSS-shRNA
Cat No 
shADV-214654
Availability
4-5 weeks

This is an Adenovirus expressing shRNA for silencing of Human LSS.

shADV-214654
Ad-h-LSS-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human LSS (lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CTRCT44; OSC
Description (Vector)
LSS catalyzes the conversion of (S)-2,3 oxidosqualene to lanosterol. The encoded protein is a member of the terpene cyclase/mutase family and catalyzes the first step in the biosynthesis of cholesterol, steroid hormones, and vitamin D. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene ID
4047
Gene Name (Vector)
lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase)
Gene Symbol
LSS
HGNC ID
HGNC:6708
ORF Size (aa)
2199
ORF Size (bp)
2199 bp
RefSeq ID
NM_001001438
RefSeq Synonyms
NM_002340, NM_001145437, NM_001145436, NM_001001438, BC035638,
Species
human
UniGene ID
Hs.596543

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.