human LOXL4 shRNA silencing Adenovirus
This is an Adenovirus expressing shRNA for silencing of Human LOXL4.
shADV-214440
Ad-h-LOXL4-shRNA
Ready-to-use Adenovirus expressing shRNA for silencing of Human LOXL4 (lysyl oxidase like 4). Available with optional GFP reporter or cell-specific promoter.
Gene Reference Data
Alternate Names
LOXC
Description (Vector)
LOXL4 encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue, encoding an extracellular copper-dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C-terminus end appears to be sufficient for amine oxidase activity, suggesting that each family member may retain this function. The N-terminus is poorly conserved and may impart additional roles in developmental regulation, senescence, tumor suppression, cell growth control, and chemotaxis to each member of the family.
Gene ID
84171
Gene Name (Vector)
lysyl oxidase like 4
Gene Symbol
LOXL4
HGNC ID
HGNC:17171
ORF Size (aa)
2271
ORF Size (bp)
2271 bp
RefSeq ID
NM_032211
RefSeq Synonyms
NM_032211, BC013153, BC007522,
Species
human
UniGene ID
Hs.671890
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About Storage Conditions
All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity.
We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.