Promotional banner reading 'FALL SAVINGS' with expiry date August 31 on an orange background; features a group of people with orange stacked blocks on the right and discounts for services and catalog products.

human TAF9B shRNA silencing Adenovirus

Name 
Ad-h-TAF9B-shRNA
Cat No 
shADV-214371
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human TAF9B.

shADV-214371
Ad-h-TAF9B-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human TAF9B (TATA-box binding protein associated factor 9b). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
DN7; DN-7; neuronal cell death-related protein 7; TAF9B RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa; TAF9L; TAF9-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 31kDa; TAFII31L; TBP-associated factor 9L; TFIID-31; transcription initiation factor IID, 31kD subunit; transcription initiation factor TFIID subunit 9B; Transcription initiation factor TFIID subunit 9-like; transcription-associated factor TAFII31L
Description (eCommerce)
Transcription initiation factor TFIID subunit 9B is essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. TAF9B may have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NP72].
Description (Vector)
Initiation of transcription by RNA polymerase II requires the activities of more than 70 polypeptides. The protein that coordinates these activities is transcription factor IID (TFIID), which binds to the core promoter to position the polymerase properly, serves as the scaffold for assembly of the remainder of the transcription complex, and acts as a channel for regulatory signals. TFIID is composed of the TATA-binding protein (TBP) and a group of evolutionarily conserved proteins known as TBP-associated factors or TAFs. TAFs may participate in basal transcription, serve as coactivators, function in promoter recognition or modify general transcription factors (GTFs) to facilitate complex assembly and transcription initiation. This gene encodes a protein that is similar to one of the small subunits of TFIID, TBP-associated factor 9, and is also a subunit of TFIID. TAF9 and TAF9b share some functions but also have distinct roles in the transcriptional regulatory process.
Gene ID
51616
Gene Name (eCommerce)
TATA-box binding protein associated factor 9b
Gene Name (Vector)
TATA-box binding protein associated factor 9b
Gene Symbol
TAF9B
HGNC ID
HGNC:17306
NCBI Taxonomy ID (eCommerce)
9606.0
ORF Size (aa)
756
ORF Size (bp)
756 bp
Protein Name (eCommerce)
Transcription initiation factor TFIID subunit 9B
RefSeq ID
NM_015975
RefSeq Synonyms
NM_015975, BC146960, BC146952, BC071649, BC010350, BC009566,
Research Areas
Apoptosis,Host-Virus Interactions,Immunology,Transcription Factor/Regulator
Research Areas (Faceted)
cell_biology,immunology,infectious_disease,transcription_translation
Species
human
Target Sentence
Transcription initiation factor TFIID subunit 9B is essential for cell viability. TAF9 and TAF9B are involved in transcriptional activation as well as repression of distinct but overlapping sets of genes. TAF9B may have a role in gene regulation associated with apoptosis. TAFs are components of the transcription factor IID (TFIID) complex, the TBP-free TAFII complex (TFTC), the PCAF histone acetylase complex and the STAGA transcription coactivator-HAT complex. TFIID or TFTC are essential for the regulation of RNA polymerase II-mediated transcription [taken from the Universal Protein Resource (UniProt) www.uniprot.org/uniprot/Q9NP72].
UniGene ID
Hs.592248
UniProt ID (eCommerce)
Q9HBM6

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.