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human SIRPB1 shRNA silencing Adenovirus

Name 
Ad-h-SIRPB1-shRNA
Cat No 
shADV-214351
Availability
7-8 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human SIRPB1.

shADV-214351
Ad-h-SIRPB1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human SIRPB1 (signal regulatory protein beta 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Validated
No
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
CD172b; SIRP-BETA-1
Description (Vector)
SIRPB1 is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. This protein was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.
Gene ID
10326
Gene Name (Vector)
signal regulatory protein beta 1
Gene Symbol
SIRPB1
HGNC ID
HGNC:15928
ORF Size (aa)
1197
ORF Size (bp)
1197 bp
RefSeq ID
NM_006065
RefSeq Synonyms
NM_006065, NM_001330639, NM_001329157, NM_001135844, NM_001083910, BC156609,
Species
human
UniGene ID
Hs.710882

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.