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human GATM shRNA silencing Adenovirus

Name 
Ad-h-GATM-shRNA
Cat No 
shADV-214197
Availability
4-5 weeks
Categories
Adenovirus, shRNA-Silencing

This is an Adenovirus expressing shRNA for silencing of Human GATM.

shADV-214197
Ad-h-GATM-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human GATM (glycine amidinotransferase). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter
U6 ()
Reporter
eGFP (default), optional CFP, YFP, RFP, mCherry
shRNA Knockdown (%)
90
shRNA Validated
Yes
Storage Buffer
DMEM, 2% BSA, 2.5% Glycerol
Viral Backbone
Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names
AGAT; AT; CCDS3
Description (Vector)
GATM encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by mental retardation, language impairment, and behavioral disorders.
Gene ID
2628
Gene Name (Vector)
glycine amidinotransferase
Gene Symbol
GATM
HGNC ID
HGNC:4175
ORF Size (aa)
1272
ORF Size (bp)
1272 bp
RefSeq ID
NM_001482
RefSeq Synonyms
NM_001482, NM_001321015, BC004141,
Species
human
UniGene ID
Hs.75335

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.