human LNX1 shRNA silencing Adenovirus

Name
Ad-h-LNX1-shRNA

Cat No
shADV-214060

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human LNX1.

shADV-214060

Ad-h-LNX1-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human LNX1 (ligand of numb-protein X 1). Available with optional GFP reporter or cell-specific promoter.

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Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

LNX; MPDZ; PDZRN2

Description (Vector)

LNX1 encodes a membrane-bound protein that is involved in signal transduction and protein interactions. The encoded product is an E3 ubiquitin-protein ligase, which mediates ubiquitination and subsequent proteasomal degradation of proteins containing phosphotyrosine binding (PTB) domains. This protein may play an important role in tumorogenesis. Alternatively spliced transcript variants encoding distinct isoforms have been described. A pseudogene, which is located on chromosome 17, has been identified for this gene.

Gene ID

84708

Gene Name (Vector)

ligand of numb-protein X 1

Gene Symbol

LNX1

HGNC ID

HGNC:6657

ORF Size (aa)

2187

ORF Size (bp)

2187 bp

RefSeq ID

NM_032622

RefSeq Synonyms

NM_032622, NM_001126328, BC034737, BC022983,

Species

human

UniGene ID

Hs.624833

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.