human LMO2 shRNA silencing Adenovirus

Name
Ad-h-LMO2-shRNA

Cat No
shADV-214037

Availability
7-8 weeks

This is an Adenovirus expressing shRNA for silencing of Human LMO2.

shADV-214037

Ad-h-LMO2-shRNA

Ready-to-use Adenovirus expressing shRNA for silencing of Human LMO2 (LIM domain only 2). Available with optional GFP reporter or cell-specific promoter.

Request a Quote

Product Details

Promoter

U6 ()

Reporter

eGFP (default), optional CFP, YFP, RFP, mCherry

shRNA Validated

Storage Buffer

DMEM, 2% BSA, 2.5% Glycerol

Viral Backbone

Human Adenovirus Type5 (dE1/E3)

Gene Reference Data

Alternate Names

RBTN2; RBTNL1; RHOM2; TTG2

Description (Vector)

LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.

Gene ID

4005

Gene Name (Vector)

LIM domain only 2

Gene Symbol

LMO2

HGNC ID

HGNC:6642

ORF Size (aa)

456

RefSeq ID

NM_005574

RefSeq Synonyms

NM_005574, NM_001142316, NM_001142315, BC073973, BC042426, BC035607, BC034041,

Species

human

UniGene ID

Hs.716597

About Storage Conditions

All our viral products should be kept at -80°C. At this temperature, the virus will remain stable for 6-12 months (and in some cases, up to 2 years). Once thawed, the product can be stored at 4°C for 2-3 weeks without significant loss of biological activity. We recommend aliquoting your vectors into low protein binding tubes upon receipt. This helps avoid repeated freeze-thaw cycles, as well as prevent loss of virus. To maintain accurate titer, aliquot in at least 20ul per tube.